Mildred Acevedo-Duncan Selected Research

PKC-3 protein

12/2021	Atypical PKCs activate Vimentin to facilitate prostate cancer cell motility and invasion.
3/2021	Roles of hepatic atypical protein kinase C hyperactivity and hyperinsulinemia in insulin-resistant forms of obesity and type 2 diabetes mellitus.
1/2020	Atypical Protein Kinase-C inhibitors exhibit a synergistic effect in facilitating DNA damaging effect of 5-fluorouracil in colorectal cancer cells.
1/2020	Effects of Atypical Protein Kinase C Inhibitor (DNDA) on Lung Cancer Proliferation and Migration by PKC-ι/FAK Ubiquitination Through the Cbl-b Pathway.
12/2019	The modulation of actin dynamics via atypical Protein Kinase-C activated Cofilin regulates metastasis of colorectal cancer cells.
2/2019	Analysis of PKC-ζ protein levels in normal and malignant breast tissue subtypes.
5/2011	A novel PKC-ι inhibitor abrogates cell proliferation and induces apoptosis in neuroblastoma.

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.

Realize the full power of the drug-disease research graph!

Mildred Acevedo-Duncan Research Topics

Disease

13	Neoplasms (Cancer) 12/2021 - 12/2004
5	Carcinogenesis 01/2020 - 11/2017
4	Neoplasm Metastasis (Metastasis) 12/2021 - 12/2019
3	Colorectal Neoplasms (Colorectal Cancer) 01/2020 - 04/2018
3	Melanoma (Melanoma, Malignant) 01/2019 - 11/2017
3	Glioma (Gliomas) 01/2019 - 12/2004
2	Prostatic Neoplasms (Prostate Cancer) 12/2021 - 11/2018
2	Hyperinsulinism (Hyperinsulinemia) 03/2021 - 04/2012
2	Type 2 Diabetes Mellitus (MODY) 03/2021 - 04/2012
2	Obesity 03/2021 - 04/2012
2	Glioblastoma (Glioblastoma Multiforme) 01/2021 - 09/2014
2	Lung Neoplasms (Lung Cancer) 01/2020 - 11/2008
2	Carcinoma (Carcinomatosis) 01/2019 - 11/2008
1	Hyperlipidemias (Hyperlipidemia) 03/2021
1	Ovarian Neoplasms (Ovarian Cancer) 01/2020
1	Urinary Bladder Neoplasms (Bladder Cancer) 01/2020
1	Breast Neoplasms (Breast Cancer) 02/2019
1	Colonic Neoplasms (Colon Cancer) 04/2018
1	Hypertriglyceridemia 04/2012
1	Hypercholesterolemia 04/2012
1	Abdominal Obesity 04/2012
1	Glucose Intolerance 04/2012
1	Metabolic Syndrome (Dysmetabolic Syndrome X) 04/2012
1	Neuroblastoma 05/2011
1	Insulin Resistance 04/2007

Drug/Important Bio-Agent (IBA)

7	PKC-3 proteinIBA 12/2021 - 05/2011
7	protein kinase C lambdaIBA 01/2020 - 02/2005
5	Protein Kinase CIBA 01/2020 - 12/2004
5	Proteins (Proteins, Gene)FDA Link 01/2020 - 12/2004
4	lysyl- arginyl- alanyl- lysyl- alanyl- lysyl- threonyl- threonyl- lysyl- lysyl- arginine (PKCS)IBA 12/2021 - 01/2020
3	Glucose (Dextrose)FDA LinkGeneric 03/2021 - 04/2007
3	Protein Kinases (Protein Kinase)IBA 01/2018 - 04/2012
2	VimentinIBA 12/2021 - 01/2018
2	Insulin (Novolin)FDA Link 03/2021 - 04/2012
2	AcidsIBA 01/2020 - 01/2018
2	Protein Isoforms (Isoforms)IBA 01/2020 - 05/2011
2	Biomarkers (Surrogate Marker)IBA 02/2019 - 11/2018
2	Phosphates (Orthophosphate)IBA 01/2018 - 05/2011
2	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 09/2014 - 11/2008
1	SodiumIBA 03/2021
1	ReninIBA 03/2021
1	AngiotensinsIBA 03/2021
1	EnzymesIBA 03/2021
1	NucleotidesIBA 01/2021
1	Temozolomide (Temodar)FDA LinkGeneric 01/2021
1	Annexin A5IBA 01/2021
1	PaxillinIBA 01/2021
1	Sirolimus (Rapamycin)FDA Link 01/2020
1	DNA (Deoxyribonucleic Acid)IBA 01/2020
1	Fluorouracil (Carac)FDA LinkGeneric 01/2020
1	Protein Serine-Threonine Kinases (Protein-Serine-Threonine Kinase)IBA 01/2020
1	Actin Depolymerizing Factors (Cofilins)IBA 12/2019
1	Actins (F Actin)IBA 02/2019
1	Indicators and Reagents (Reagents)IBA 02/2019
1	imidazoleIBA 01/2019
1	CateninsIBA 04/2018
1	NucleosidesIBA 01/2018
1	protein kinase C zetaIBA 01/2018
1	3,4-diaminonaphthalene-2,7-disulfonic acidIBA 11/2017
1	LigandsIBA 09/2014
1	FITC-annexin A5IBA 09/2014
1	Caspase 3 (Caspase-3)IBA 09/2014
1	Gold Sodium Thiomalate (Sodium Aurothiomalate)IBA 04/2012
1	Phosphotransferases (Kinase)IBA 04/2012
1	CarbohydratesIBA 04/2012
1	LipidsIBA 04/2012
1	Pharmaceutical PreparationsIBA 05/2011
1	AndrogensIBA 11/2008
1	HexosaminesIBA 04/2007
1	Cyclin-Dependent Kinase-Activating KinaseIBA 02/2005
1	aloe emodinIBA 12/2004
1	IsoenzymesIBA 12/2004
1	Dimethyl Sulfoxide (DMSO)FDA LinkGeneric 12/2004

Therapy/Procedure

4	Therapeutics 01/2021 - 09/2014
1	Drug Therapy (Chemotherapy) 01/2021